Notre Dame core facility acquires new single-cell sequencing equipment

Author: Brandi Klingerman

10x Side View The Chromium Controller from 10X Genomics will be available at the Genomics and Bioinformatics Core Facility.

The Genomics and Bioinformatics Core Facility (GBCF) at the University of Notre Dame is now offering researchers access to a new instrument with applications for cell biology, cancer, immunology, and neuroscience research. 

Called the Chromium Controller from 10X Genomics, the tool is a massive sample partitioning and molecular barcoding system that enables thousands of micro-reactions in parallel, allowing the discovery of gene expression dynamics and molecular profiling of individual cell types, elucidation of gene regulatory mechanisms, study of disease pathogens, and characterization of genomic structure.

“The ability to examine genomic and transcriptomic patterns at the level of single cells is rapidly becoming an essential tool in biological investigation. Researchers interested in this piece of equipment or our other core services are invited to reach out to learn more about our facility,” said Melissa Stephens, assistant director of the GBCF. “Our facility is ready to help labs integrate this new technology into their research plans.” 

The 10X Genomics tool complements existing equipment at the GBCF, which provides comprehensive services and support for state-of-the-art 'omics'​ experiments and bioinformatics analysis. The facility welcomes users at Notre Dame and beyond.

Cost share funding for the new instrument was provided by the Eck Institute for Global Health, the Harper Cancer Research Institute, the Boler-Parseghian Center for Rare and Neglected Diseases, and the Center for Stem Cells and Regenerative Medicine.

To learn more about the GBCF and their services, please visit http://genomics.nd.edu/

Contact:

Melissa Stephens / Assistant Director

Genomics and Bioinformatics Core Facility / University of Notre Dame

stephens.49@nd.edu / 574.631.0338

About Notre Dame Research:

The University of Notre Dame is a private research and teaching university inspired by its Catholic mission. Located in South Bend, Indiana, its researchers are advancing human understanding through research, scholarship, education, and creative endeavor in order to be a repository for knowledge and a powerful means for doing good in the world. For more information, please see research.nd.edu or @UNDResearch.